Pharmaceutical Intermediates White Miconazole Nitrate CAS 22832-87-7 CAS NO.22832-87-7

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Top Quality Anti-Inflammatory Pharmaceutical Raw Materials Miconazole Nitrate CAS 22832-87-7

Abstract

Anti-inflammatory or antiinflammatory refers to the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system.

Non-steroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. On its own, COX enzyme synthesizes prostaglandins, creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the pain.

Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs even though they presumably share the same mode of action.

On the other hand, there are analgesics that are commonly associated with anti-inflammatory drugs but that have no anti-inflammatory effects. An example is paracetamol (known as acetaminophen in the U.S). As opposed to NSAIDs, which reduce pain and inflammation by inhibiting COX enzymes, paracetamol has - as early as 2006 - been shown to block the reuptake of endocannabinoids, which only reduces pain, likely explaining why it has minimal effect on inflammation.

Usage

1. For serious infections caused by Candida species, including peritonitis, pneumonia and bladder infections. Miconazole nitrate can also be used for the treatment of the secondary infection due to the Gram-positive bacteria.

2. The area administration can be used treating chronic and extensive mucocutaneous candidiasis, vulvovaginitis candidiasis, tinea, ringworm, jork itch, athlete’s foot, tinea versicoeor and paronychomycosis due to various kinds of dermatophytes, yeast as well as other kinds of fungus.

3. Intravenous administration from it can be used for treating serious cryptococcosis, coccidioidomycosis and vice coccidioidomycosis.