GHRP-2 Pralmorelin 5mg 10mg Lyophilized Peptide High Purity GHRP-2 Growth Hormone Release Peptide-2 CAS NO.158861-67-7

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GHRP-2(5mg/vial & 10mg/vial)Detailed Specifications:

Appearance: White Lyophilized Powder

Purity (HPLC): 98.0%min

Single Impurity (HPLC): 1.0%max

Amino Acid Composition: ±10% of theoretical

Peptide Content (N%): ≥80.0%

Water Content(Karl Fischer): ≤6.0%

Acetate Content (HPIC): ≤12.0%

MS(ESI): Consistent

Mass Balance: 95.0~105.0%

Payment & Shipping Terms:

Mini Order: 10 vials
Price: Negotiable
Packaging Details: Super discreet to ensure 100% pass rate

Lead Time: Within 24 hours after payment confirmed

Delivery: Average 6 days / Door-to-Door
Payment Terms: T/T, , Money Gram, Bitcoin
Supply Ability: 10000 vials/month

Description and Applications:

Growth Hormone Releasing Peptide 2, GHRP-2, is a synthetic agonist of ghrelin, the newly-discovered gut peptide which binds to the (GH) secretagogue receptor. Ghrelin has two major effects, stimulating both GH secretion and appetite meal initiation. GHRP-2 has been extensively studied for its utility as a secretagogue (GHS). Animal studies have shown its effect on food intake. However, whether GHRP-2 can also stimulate appetite in humans when administered acutely is not known. We subcutaneously infused 7 lean, healthy males with GHRP-2 (1 microg/kg/h) or saline for 270 minutes and then measured their intake of an ad libitum, buffet-style meal. These data are the first to demonstrate that GHRP-2, like ghrelin, increases food intake, suggesting that GHRP-2 is a valuable tool for investigating ghrelin effects on eating behavior in humans.

GHRP-2 is a 2nd generation GHRP just behind GHRP-6. Compared to GHRP-6, GHRP-2 is

considered to be much more superior in terms of growth hormone stimulation because over longer

periods of time it maintains maximum elevations in Growth Hormone. GHRP-2 has shown

to increase IGF-1 levels (Insulinlike Growth Factor 1), and even greater results happen when

used with Growth Hormone Releasing Hormone (GHRH). It has a short half life withpeak

concentrations occurring around 15 minutes but not longer than 60 minutes. The response of

natural physiologic system includes increase in levels of calcium ion influx alongside with increased

release of growth hormones in response to the high-amplitude pulsation from the GHRP-2. GHRP-2

and other ghrelin analogues increase the number of somatotropes involved in the GH pulse by

inhibiting somatostatin, GHRH increases the pulse amplitude per pituitary cell or somatotrope by

other means. Unlike ghrelin, GHRP-2 is not lipogenic which means that it does not induce fat storage.

Although ghrelin plays a large role in hunger, GHRP-2 as an analog of ghrelin does not increase

appetite significantly.

GHRPs are not simply surrogates of GHRH, instead GHRP-6 is an artificial activator of a separate

newly discovered receptor called Secretagogue Receptor (GHS-R). Soon Ghrelin was discovered, the endogenous ligand that binds to the GHS-R. Both Ghrelin and all the synthetic compounds such as GHRP-6 were termed "Secretagogues" (GHSs). One side effect of GHRP-6 is a significant increase in appetite due to stimulating the release of Ghrelin, a peptide that is released naturally in the lining of

the stomach that increases hunger and gastric emptying. Also, GHRP-6 causes stimulation of the

anterior pituitary gland which causes an increase in release. The increased amounts of Hormone can cause the liver to secrete the hormone , which improves the animal body's ability to burn fat and build muscle. Since GHRP-6 acts directly on the feedback loop which signals the inhibition of Hormone

release, GHRP-6 can re-stimulate the production of Hormone.