China (Mainland)
Amlodipine Besylate Pharmaceutical Raw Materials 111470-99-6 Treat For Hypertension CAS NO.111470-99-6
- Min.Order: 1 Gram
- Payment Terms: T/T,MoneyGram,Other
- Product Details
Keywords
- Amlodipine Besylate
- 111470-99-6
- Pharmaceutical Raw Materials
Quick Details
- ProName: Amlodipine Besylate Pharmaceutical Raw...
- CasNo: 111470-99-6
- Appearance: white powder
- Application: for research
- DeliveryTime: product will be sent out with in 24 ho...
- PackAge: according to the customers requriement...
- Port: shanghai, shenzhen,hongkong
- ProductionCapacity: 1 Metric Ton/Week
- Purity: 99.9%
- LimitNum: 1 Gram
- Moisture Content: 0.005%
- Impurity: 0.005%
Superiority
Price,company and service advantage:
1. Best service, high quality and reasonable price
2. It's customers' right to choose the package (EMS, DHL, FedEx, UPS);
3. It's customers' right to choose the packing way for his produccts from many
recent effective packing ways
4. Specials are possible when client's order is big enough, including the discount policy;
5. Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time;
6. We can help our regular clients to suggest some vials factories which produce different size vials(2ml, 5ml, 7ml, 10ml, 20ml...), hoping can bring you convenience if you need these vials, too.
7. Return policy: we promise we will return your money if our product don't have effect.
Details
Amlodipine Besylate Pharmaceutical Raw Materials 111470-99-6 Treat
For Hypertension
Amlodipine
Amlodipine MW: 567.05
Amlodipine Chemical Properties Yellow Solid
Amlodipine Usage
1.A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
2. Anti-hypertensive;calcium channel blocker
3.Long-acting dihydropyridine calcium antagonists. For high blood pressure, may be used alone or in combination with other anti-hypertensive drug can also be used in patients with stable angina pectoris.
4.For the treatment of hypertension and stable angina pectoris.
Product Name: Amlodipine besylate
Chinese name: amlodipine besylate
Synonyms: 2 [(2-aminoethoxy) methyl] -4 (2-chlorophenyl) -3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl- 3-ethyl-5-methyl-2- (2-aminoethoxymethyl) -4- (2-chlorophenyl) -1,4-benzopyridine benzenesulfonate; Dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulfonate; amlodipine besylate (lycopene), amlodipine besylate (standard); benzene Amlodipine sulfonate (Amlodipine besylate, lycopene), arropline sulfonate; amlodipine besylate 1KG
English name: Amlodipine besilate
Amlodipine CAS Number: 111470-99-6
Amlodipine Molecular formula: C26H31ClN2O8S
Amlodipine Molecular weight: 567.05
Amlodipine CAS: 111470-99-6
Amlodipine Standard: BP
Amlodipine Level: Pharmaceutical grade
Amlodipine Content: 99%
Amlodipine Appearance: white powder
Amlodipine Packing: 25 kg / plastic bucket
Ingredients: Amlodipine besylate 99
Physical and chemical properties: soluble in methanol, slightly soluble in water.
Category: Pharmaceutical raw materials
Submerged products: Amlodipine besylate tablets
Use: Dihydropyridine calcium antagonists (calcium antagonists or slow channel blockers).
Dosage: 5-10mg, once a day
Amlodipine COA:
| Items | Tests | Results | |
| Appearance | White powder | White powder | |
| Solubility | Slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol, slightly soluble in 2-propanol. | complies | |
| Identification |
A.The IR spectrum should be concordant with IR spectrum of the RS B.Identity test C. Identity test |
complies | |
| Optical rotation | -0.10º to + 0.10º | 0.01 º | |
| Water | Not more than 0.5% | 0.2% | |
| Residue on ignition | Not more than 0.2% | 0.1% | |
| Heavy metals | Not more than 0.002% | Less than 0.002% | |
| Related substances |
A. TLC - any impurity - nmt 0.3% - not more than two impurities - not more than 0.1 B. liquid chromatography - impurity D - nmt 0.3% - total impurities - nmt 0.3% |
complies ND 0.28% | |
| Assay | It contains not less than 98.0% and not more than 102.0% of C26H31ClN2O8S calculated with reference to the dried substance. | 99.3% | |
| Conclusion | Conforms to EP standards. | ||
more detail:
| Chemical Properties | White Crystalline Solid |
| Usage | A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive |
| Usage | Angiotensin II inhibitor prodrug, antihypertensive |
| Usage | Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats. |
What is amlodipine
Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.
Amlodipine is used to treat chest pain (angina) and other conditions caused by coronary artery disease.
Amlodipine is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.
Amlodipine is for use in adults and children who are at least 6 years old.
